Twenty First
Our verdict
Twenty First occupies a considered address on 21st Avenue South in Nashville's Hillsboro Village corridor, a stretch that has grown into one of the city's more serious dining destinations. The venue sits in a neighbourhood defined by independent operators and a local-first sensibility, positioning it closer to the progressive independent tier than to the Broadway-adjacent crowd pleasers.
Pearl is the En Primeur Club membership app — saves, bookings, and concierge access live there. Same editors, same standards.
- Address
- 1602 21st Ave S, Nashville, TN 37212
- Phone
- (615) 623-9767
- Hours
- Mon ClosedTue–Thu 11 AM–9 PMFri 10 AM–10 PMSat 10 AM–2 PM, 5–10 PMSun 10 AM–9 PM
- Website
- twentyfirstnashville.com
- Directions
- Get directions
- Booking
- Book on OpenTable

The menu
What to order
- Girl Dinner
- Crab Arancini
- Hot Chicken Sandwich
A Street, a Space, a Posture
21st Avenue South runs through Hillsboro Village with the quiet confidence of a neighbourhood that doesn't need to announce itself. The stretch between Vanderbilt's campus edge and the 12 South corridor has accumulated, over the past decade, a particular kind of operator: independent, considered, resistant to the neon-and-honky-tonk gravity of lower Broadway. Twenty First takes its name and its address from that street, which is less a coincidence than a declaration of where it places itself within Nashville's dining geography.
The physical address at 1602 21st Ave S puts Twenty First within walking distance of a concentration of independent restaurants that have collectively shifted how Nashville is read by food-focused visitors. This is not the tourist corridor. Arriving on foot from the surrounding residential blocks, the transition from neighbourhood street to dining destination is gradual rather than theatrical — the building presents itself without marquee ambition, which in this part of town reads as confidence rather than restraint.
The Space as Editorial Statement
In American dining, the interior of a restaurant communicates its intentions before the menu arrives. The shift away from tablecloth formality toward raw material and considered geometry — concrete, reclaimed wood, open kitchens set into exposed brick, characterises the aesthetic register that Nashville's more serious independents have largely adopted since the mid-2010s. The design language signals a particular value system: craft over comfort, transparency over theatre, the work visible rather than concealed behind ceremony.
Twenty First sits within this broader design moment in American restaurant architecture. The Hillsboro Village address places it in a built environment that favours converted retail and low-rise mixed-use over purpose-built dining rooms, which tends to produce spaces with idiosyncratic proportions, rooms that feel earned rather than constructed. How that translates into seating arrangements and spatial hierarchy at Twenty First specifically is something leading assessed in person, but the neighbourhood context shapes expectations: smaller counts, closer quarters, and an atmosphere calibrated for conversation rather than spectacle.
This matters because seating arrangements in independently operated restaurants at this tier function as a form of editorial curation. A lower seat count signals a decision about pacing, about the ratio of kitchen output to table turns, about what kind of evening the operator is designing. Nashville's progressive independent tier, venues like Locust and The Catbird Seat, has generally favoured intimacy over volume, and Twenty First occupies a neighbourhood where that orientation is the norm rather than the exception.
Nashville's Independent Dining Tier in 2024
Nashville has earned a more complex national dining reputation than its tourism profile might suggest. The city's independent restaurant scene has developed a credible progressive tier, with a handful of operators working at a level of ambition and execution that invites comparison with more established American fine-dining cities. Bastion, operating at the $$$$ tier with a contemporary format, and Peninsula, in the Southern American register, represent the kind of locally rooted ambition that has made Nashville worth the attention of food-focused travellers who might otherwise default to New York, Chicago, or San Francisco.
At the national level, the reference points for serious American dining remain concentrated on the coasts and in Chicago: Alinea, Le Bernardin in New York City, The French Laundry in Napa, Providence in Los Angeles, Blue Hill at Stone Barns in Tarrytown, and Addison in San Diego have set the benchmark for what American fine dining can achieve at its upper register. What Nashville's better independents offer is something different: a dining culture less freighted by that particular legacy, where the conversation is about Southern identity, ingredient sourcing, and a hospitality register that is warmer and less performatively precise than what you'd encounter at The Inn at Little Washington or Atomix in New York City.
That proximity shapes the competitive context: these are neighbourhood operators competing on consistency, local loyalty, and the quality of the room as much as on the ambition of the kitchen.
Placing Twenty First Within Nashville's Dining Conversation
The trajectory of American restaurant design over the past decade has moved toward legibility, spaces that communicate their intentions clearly, where the materials and proportions tell you something true about what you're about to eat and how long you should expect to spend eating it. Nashville's Hillsboro Village corridor has been a consistent site of that experiment, with operators who have chosen neighbourhood depth over tourist volume.
For comparison, the progressive registers in other American cities have produced formats that emphasise the experience architecture as much as the food: Lazy Bear in San Francisco with its communal long-table structure, Single Thread Farm in Healdsburg with its farm-to-kitchen verticality. The southern American equivalent tends to be less conceptually scaffolded and more directly expressive, the room as a genuine reflection of place rather than a designed container for a concept.
Internationally, the conversation around restaurant design as a primary carrier of identity has been explored at venues like 8 1/2 Otto e Mezzo Bombana in Hong Kong and Emeril's in New Orleans, each of which uses its physical presence to anchor a particular version of what dining in that city should feel like. Twenty First, on its quieter Nashville block, is participating in a version of that same conversation, at a different scale and with different reference points.
For visitors building a Nashville itinerary around serious independent dining, the Hillsboro Village and 12 South axis is the sensible anchor. Our full Nashville restaurants guide maps the broader scene across neighbourhood and format, which is useful context for placing Twenty First within the city's current dining geography.
Planning Your Visit
Twenty First is located at 1602 21st Ave S, in the Hillsboro Village area of Nashville. The address is accessible by car with street parking available on surrounding residential blocks, and the neighbourhood is walkable from Vanderbilt University's campus. For dining in this corridor, arriving with a reservation is standard practice among the better-regarded independents; the Hillsboro Village cluster draws both local regulars and visiting diners, and walk-in availability on weekend evenings is not something to rely on. Timing a visit for a weeknight reduces friction and generally produces a quieter room.
Frequently asked questions
Is Twenty First okay with children?
Hillsboro Village is a mixed residential and commercial neighbourhood with a broad demographic range, and independent restaurants in this area generally accommodate families during earlier service windows.
What's the overall feel of Twenty First?
Twenty First sits within a neighbourhood defined by independent operators and a local-first orientation, which shapes the atmosphere toward the considered rather than the performative. Hillsboro Village, unlike Nashville's higher-traffic dining zones, attracts guests who live nearby or seek it out deliberately. The posture is closer to a neighbourhood room than a destination showcase.
How does Twenty First compare to other independent restaurants along Nashville's 21st Avenue South corridor?
21st Avenue South has positioned itself as one of Nashville's more consistent independent dining streets, distinct from the Gulch and 12 South in that it draws a higher proportion of residential regulars than out-of-town visitors. Twenty First at 1602 21st Ave S occupies that same local-first tier, placing it alongside operators whose continuity comes from repeat neighbourhood custom rather than review-cycle tourism. For visitors, that distinction usually translates to a more grounded dining room.
What should I eat at Twenty First?
Menu specifics are best confirmed directly with the venue, as independent operators at this level in Nashville typically adjust offerings based on season and sourcing. The Hillsboro Village corridor has a track record of kitchens that follow product availability rather than fixed menus, so calling ahead or checking current offerings before visiting is the practical approach.
What's Twenty First's location?
Twenty First is located at 1602 21st Ave S, Nashville, TN 37212, Nashville.
Should I book Twenty First in advance?
For independently operated restaurants in Nashville's serious dining tier, booking ahead is the sensible approach. The Hillsboro Village corridor draws both neighbourhood regulars and visitors specifically seeking alternatives to the Gulch and Broadway tourism belt, which compresses availability at smaller operators. Reservations or a direct call before arriving will save a wasted trip.
What is Twenty First known for?
Twenty First is associated with the independent dining corridor on 21st Avenue South in Nashville's Hillsboro Village. This stretch has developed a reputation for operator-driven restaurants that prioritise neighbourhood consistency over high-volume tourism. The address at 1602 21st Ave S places it within a cluster of locally oriented businesses that define the area's character.
At a Glance
Comparable venues nearby, for context on price, style, and recognition.
| Venue | Cuisine | Price | Notes |
|---|---|---|---|
| Twenty FirstThis venue — the venue you are viewing | Modern American Contemporary | $30–50 | Not listed |
| L.A. Jackson | Modern American Small Plates | $30–50 | Music Row, Modern American Small Plates |
| 5th & Taylor | Modern American | $50–100 | Germantown, Modern American |
| House of Cards | Classic American Steakhouse with Magic | $50–100 | Downtown, Classic American Steakhouse with Magic |
| Black Rabbit | Modern American Grill | $50–100 | Capitol Hill Area, Modern American Grill |
Continue exploring
More in Nashville
Restaurants in Nashville
Browse all →Bars in Nashville
Browse all →Hotels in Nashville
Browse all →Wineries in Nashville
Browse all →Details
- Modern
- Elegant
- Cozy
- Sophisticated
- Date Night
- Group Dining
- Casual Hangout
- Open Kitchen
- Craft Cocktails
- Local Sourcing
- A La Carte
- Small Plates
- Craft Cocktails
- Vegetarian Friendly
Current opening hours
- Monday
- Closed
- Tuesday
- 11 AM–9 PM
- Wednesday
- 11 AM–9 PM
- Thursday
- 11 AM–9 PM
- Friday
- 10 AM–10 PM
- Saturday
- 10 AM–2 PM, 5–10 PM
- Sunday
- 10 AM–9 PM
Hours can change for holidays and private events. Last verified .
Warm, welcoming, and cozy atmosphere well-suited for gathering with friends and family.















