Nesso Italian Kitchen
Wine Spectator Award of Excellence
Our verdict
Nesso occupies a deliberate position in Indianapolis's evolving bar scene, drawing attention through the depth and curation of its spirits program rather than spectacle. Located at 339 S Delaware St in downtown Indianapolis, it represents the city's shift toward collection-driven drinking culture, where what's behind the bar matters as much as what's in the glass.
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- Address
- 339 S Delaware St, Indianapolis, IN 46204
- Phone
- (317) 643-7400
- Hours
- Mon–Sat 5–10 PMSun 4–9 PM
- Website
- nesso-italia.com
- Directions
- Get directions
- Booking
- Book on OpenTable

A Different Kind of Drinking in Downtown Indianapolis
Walk into most bars on a Friday night in Indianapolis and the back bar is decoration. Bottles arranged for symmetry, backlit for effect, chosen for familiarity. Nesso, at 339 S Delaware St in the city's downtown core, operates on a different premise: the spirits program is the point, not the backdrop. The room asks you to pay attention to what you're drinking, and that shift in priority puts it in a specific, smaller category of American bar programs where curation does the heavy lifting.
This is not the dominant mode of drinking in the Midwest. Indianapolis has a lively and growing bar culture, but the city's most-visited spots tend to skew toward approachability and volume. Places like 317 Burger and Alley Cat Lounge serve their own purposes well. Nesso belongs to a narrower conversation, one that places Indianapolis alongside cities where collection-led bar programs have taken hold as a serious format.
The Logic Behind a Collection-Driven Bar
In American cocktail culture, the past decade has produced two diverging tendencies. On one side, bars have moved toward technical discipline: clarified drinks, precise dilution, house-made ingredients, and a cocktail menu that functions almost like a tasting menu. On the other, a smaller group of programs has built identity around what sits on the shelf rather than what gets built in the shaker. These are bars where the depth of the back bar, the breadth of rare bottles, and the knowledge required to navigate them define the experience.
The latter format demands more from both the operator and the guest. A curated spirits program requires sourcing relationships, significant investment in inventory, and staff who can speak credibly about provenance, distillation method, production region, and age. When it works, it creates a different kind of evening: one where the conversation moves between guest and bartender as much as between guests, and where the drink in your glass is a specific argument about a specific category.
Programs of this kind have found serious footing in cities with established cocktail cultures. Kumiko in Chicago built its reputation on Japanese whisky depth and precise hospitality. Jewel of the South in New Orleans anchors its identity in historical drink research and rare spirits access. ABV in San Francisco has long operated as a reference point for amaro and bitter spirit collections. Nesso enters that broader category of collection-led programs, applying the format to a city that has not historically been associated with it.
What the Back Bar Tells You
The editorial angle on any collection-driven bar begins with what's on the shelf, and specifically what the selection reveals about the program's priorities. A back bar assembled around depth rather than breadth signals deliberate restraint: fewer categories covered in real detail rather than every category represented superficially. The opposite, a shelf of familiar commercial bottles broken up by a few trophy acquisitions, tells a different story about intent.
Internationally, bars that have built serious reputations on spirits curation share certain characteristics: a defined point of view about which categories deserve depth, buying patterns that track allocation releases and small-producer runs, and a service model where staff are expected to guide guests through the selection rather than simply execute orders. Bar Leather Apron in Honolulu operates this way with Japanese spirits. The Parlour in Frankfurt applies similar logic to gin and aged spirits in a European context. The format translates across geographies when the underlying commitment to the collection is genuine.
At Nesso, the downtown address at 339 S Delaware St places it within reach of Indianapolis's professional and after-work dining circuit, which shapes who comes through the door and what they're looking for. A collection-led program in this location functions differently than one in a more nightlife-oriented neighborhood: the guest is more likely to be interested in a considered drink than a fast one, which suits the format.
Nesso in the Indianapolis Bar Context
Indianapolis's bar scene has matured considerably. The city now has enough range that visitors can move from neighborhood taverns to cocktail-forward programs to spirits-focused bars without significant effort. That range is what makes Nesso's position legible: it occupies the more specialist end of that spectrum, in the same way that Almost Famous or Aristocrat Pub and Oxford Room each occupy distinct positions along it.
It competes for the same guest who might, in another city, walk into Julep in Houston for American whiskey depth or Superbueno in New York City for an agave-forward program with genuine category knowledge. The question in each case is the same: does the bar know its collection well enough to justify the premium on your time and attention?
That question matters more in Indianapolis than in cities where collection-led bars are common, because the guest arriving at Nesso is making a more deliberate choice. The format is less expected here, which raises the stakes on delivery.
Planning a Visit
Nesso sits at 339 S Delaware St in downtown Indianapolis, accessible from the central business district on foot and within reasonable distance of the city's main hotel corridor. For those building a broader evening around the area, the downtown dining circuit offers genuine range before or after. Our full Indianapolis restaurants guide covers the broader options across neighborhoods and price points.
For a spirits-focused program of this kind, visiting midweek gives you more access to staff attention, which is where the value of a collection-led bar is actually delivered. Coming in on a quieter night and working through a category with someone who knows the shelf is a different experience from ordering the first thing that sounds familiar on a crowded weekend.
Frequently asked questions
What part of town is Nesso in?
Nesso is located at 339 S Delaware St, Indianapolis, IN 46204, Indianapolis.
How does Nesso fit into Indianapolis's cocktail scene compared to other serious bars in the city?
Indianapolis's cocktail scene has developed enough range over the past several years to support bars with distinct, program-specific identities rather than broad appeals. Nesso's position at 339 S Delaware St in the central business district puts it within the tier of cocktail-forward destinations that reward repeat visits — the kind of bar where the selection evolves and the conversation about what's on the shelf is part of the experience, not incidental to it.
What's the best thing to order at Nesso?
The short answer is to follow what the bar is built around: the back bar. At a collection-driven program like Nesso's at 339 S Delaware St, the most rewarding orders tend to be drinks that put a specific bottle or producer at the center rather than masking it. Ask the bartender what's come in recently or what they'd highlight from the shelf — that question will tell you more than scanning a menu.
What's the main draw of Nesso?
The draw is the collection itself and the programming built around it. Where most downtown Indianapolis bars treat the back bar as visual wallpaper, Nesso's approach treats the shelf as the editorial argument — bottles chosen for what they say about a category, a region, or a producer rather than for margin or familiarity. That's a different contract with the guest than you'll find at the majority of cocktail bars in the city.
Should I book Nesso in advance?
For a bar operating at this level of specificity in a maturing scene like Indianapolis, walk-in availability on weekend evenings is worth checking ahead rather than assuming.
In Context: Similar Options
| Venue | Cuisine | Price |
|---|---|---|
| Livery | Latin-Inspired Tapas | $30–50 |
Recognition history
Dated appearances from independent guides and award organizations, with the underlying list record or original source where available.
Wine Spectator Award of Excellence
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